Organometallic Compounds
Medchemexpress LLC Abemaciclib (methanesulfonate) | 1231930-82-7 | 99.8% | 602.70 | 200 MG
This compound is a selective and BBB-permeable inhibitor of CDK4/6, with half-maximal inhibitory concentrations (IC50s) of 2 nM and 10 nM for CDK4 and CDK6, respectively.
- Selective inhibition of key enzymes involved in cell cycle regulation.
- Permeates the blood-brain barrier.
- Reduces cell viability in various human cell lines, including HCT-116, MCF7, and PANC-1.
- Inhibits Rb phosphorylation, leading to a G1 arrest and suppressed proliferation.
- Activity is specific for cells that are proficient in Rb.
- Effective in reducing cell viability across multiple cancer cell lines.
- Demonstrates antiproliferative activity against human HCT116 and MCF7 cells.
- Shows inhibition in resistant cell lines.
- Causes a cooperative antitumor effect when combined with other agents in xenograft models.
- Leads to significant tumor growth inhibition in xenograft models.
Sigma Aldrich Fine Chemicals Biosciences Clobetasol propionate for
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
![eMolecules 26386-88-9 | Diphenyl phosphoryl azide | Chem-Impex | MFCD00001987 | 275.204 | C12H10N3O3P | 99.000 | [N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1 | 250g | 112443059](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471705.jpg-250.jpg)
eMolecules 26386-88-9 | Diphenyl phosphoryl azide | Chem-Impex | MFCD00001987 | 275.204 | C12H10N3O3P | 99.000 | [N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1 | 250g | 112443059
Diphenyl phosphoryl azide | Chem-Impex | 26386-88-9 | MFCD00001987 | 275.204 | C12H10N3O3P | 99.000 | [N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1 | 250g | 112443059
eMolecules 26386-88-9 | Diphenyl phosphoryl azide | Chem-Impex | MFCD00001987 | 275.204 | C12H10N3O3P | 99.000 | [N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 112443056
Diphenyl phosphoryl azide | Chem-Impex | 26386-88-9 | MFCD00001987 | 275.204 | C12H10N3O3P | 99.000 | [N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 112443056
eMolecules 431-35-6 | 3-BROMO-1,1,1-TRIFLUOROACETONE | AstaTech | MFCD00039237 | 190.947 | C3H2BrF3O | 98.000 | FC(F)(F)C(=O)CBr | 100g | 392638049
3-BROMO-1,1,1-TRIFLUOROACETONE | AstaTech | 431-35-6 | MFCD00039237 | 190.947 | C3H2BrF3O | 98.000 | FC(F)(F)C(=O)CBr | 100g | 392638049